Pregnant women, people with chronic conditions and those in contact with people with weakened immune systems are currently being invited by their GP practices to be vaccinated.
They are being seen first because they are most at risk from swine flu and its complications. Frontline health and social care workers are also being vaccinated.
Commenting, Lesley Griffiths AM said:
"I would urge all those eligible for the vaccine to take up the option as soon as possible.
"The vaccine has been tested and approved and is the best way to protect people from the virus.
"I would like to see a 100% take-up of the vaccine to protect communities in Wrexham and across Wales.
"For those not yet entitled to the vaccine the advice is to stay at home if you have flu-like symptoms.
"You can check the symptoms by calling the swine flu information line on 0800 1 513 513."
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